Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Addison's disease without pigmentation.

C J Runcie, C G Semple, S D Slater

    Scottish Medical Journal
    |April 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Addison's disease can be difficult to diagnose when patients lack typical skin darkening. This study highlights four cases where delayed diagnosis occurred due to the absence of pigmentation, emphasizing the need for broader diagnostic considerations.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Assessing the performance of a consultant anaesthetist by control chart methodology.

    Anaesthesia·2009
    Same author

    Cancer incidence and mortality in patients with insulin-treated diabetes: a UK cohort study.

    British journal of cancer·2005
    Same author

    Birthweight and other pregnancy outcomes in a cohort of women with pre-gestational insulin-treated diabetes mellitus, Scotland, 1979-95.

    Diabetic medicine : a journal of the British Diabetic Association·2005
    Same author

    Mortality of South Asian patients with insulin-treated diabetes mellitus in the United Kingdom: a cohort study.

    Diabetic medicine : a journal of the British Diabetic Association·2004
    Same author

    Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes.

    Diabetologia·2003
    Same author

    Insulin-induced hypoglycemia induces a rise in C-reactive protein.

    Diabetes care·2000
    Same journal

    Association of inflammation with sex hormones and vitamin D in women: Findings from NHANES (2021-2023).

    Scottish medical journal·2026
    Same journal

    The future of large language models in clinical and academic medicine.

    Scottish medical journal·2026
    Same journal

    ICDMS: Integrating multimodal data for intelligent clinical decision-making in healthcare: Current trends and future directions.

    Scottish medical journal·2026
    Same journal

    Evaluation of large language models with clinical guidance for vetting outpatient magnetic resonance imaging lumbar spine referrals.

    Scottish medical journal·2026
    Same journal

    Improving access and reducing patient travel burden through telehealth: A quality improvement report from NHS Scotland.

    Scottish medical journal·2026
    Same journal

    Scottish Cardiac Society 34th Annual General Meeting Thursday 2 & Friday 3 October 2025.

    Scottish medical journal·2026
    See all related articles

    Area of Science:

    • Endocrinology
    • Internal Medicine
    • Medical Diagnostics

    Background:

    • Addison's disease, or primary adrenal insufficiency, is often associated with hyperpigmentation.
    • Diagnostic delays can lead to severe health consequences, including adrenal crisis.

    Observation:

    • This report details four cases of Addison's disease.
    • In these individuals, the absence of characteristic skin pigmentation complicated and delayed the diagnosis.

    Findings:

    • The lack of hyperpigmentation in these four patients led to unexpected or dangerously delayed diagnosis of Addison's disease.
    • This challenges the traditional diagnostic criteria that rely heavily on skin changes.

    Implications:

    • Clinicians should consider Addison's disease even in the absence of pigmentation.

    Related Experiment Videos

  • Broadening diagnostic awareness is crucial for timely intervention and improved patient outcomes in primary adrenal insufficiency.