Establishment of a controlled induced pluripotent stem cell line SDPHi004-A from a healthy male donor
Ziwen Feng1, Xiaomeng Yang2, Haiyan Zhang2
1First School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, Shandong, China; Tumor Minimally Invasive Comprehensive Treatment Department, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Ji'nan 250021, China; Pediatric Research Institute, Children's Hospital Affiliated to Shandong University, Ji'nan 250022, China.
Abstract:
The current induced pluripotent stem cell (iPSCs) line was created from peripheral blood mononuclear cells (PBMCs) obtained from a male donor who was in good health.The iPSCs line SDPHi004-A exhibited the expression of pluripotency markers, absence of free type vectors, maintenance of a normal karyotype, and potential for in vitro trilineage differentiation.This cell line could provide a foundation for disease modeling and facilitate further investigation into the molecular pathogenesis.
