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Updated: Jul 25, 2025

Assessment of Human Natural Killer Cell Events Driven by FcγRIIIa Engagement in the Presence of Therapeutic Antibodies
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The complement system in IgAN: mechanistic context for therapeutic opportunities

Anna Duval1,2, Sophie Caillard2, Véronique Frémeaux-Bacchi1,3

  • 1Centre de Recherche des Cordeliers, Inserm UMR S1138, Paris, France.

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
|June 29, 2023
PubMed
Summary

The complement system contributes to kidney damage in IgA nephropathy (IgAN). This review explores complement activation mechanisms and therapeutic inhibition strategies for IgAN progression.

Keywords:
IgA nephropathycomplementcomplement inhibitorsglomerulonephritistherapeutics

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