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Updated: Jul 25, 2025

Measuring Interactions of Globular and Filamentous Proteins by Nuclear Magnetic Resonance Spectroscopy NMR and Microscale Thermophoresis MST
Published on: November 2, 2018
A Monte Carlo algorithm to improve the measurement efficiency of low-field nuclear magnetic resonance
Pan Guo1, Ruoshuang Zhang2, Jiawen Zhang2
1College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing, China. guopan@cqnu.edu.cn.
Abstract:
Nuclear magnetic resonance (NMR) has shown good applications in engineering fields such as well logging and rubber material ageing assessment. However, due to the low magnetic field strength of NMR sensors and the complex working conditions of engineering sites, the signal-to-noise ratio (SNR) of NMR signals is low, and it is usually necessary to increase the number of repeated measurements to improve the SNR, which means a longer measurement time. Therefore, it is especially important to set the measurement parameters appropriately for onsite NMR. In this paper, we propose a stochastic simulation using Monte Carlo methods to predict the measurement curves of [Formula: see text] and [Formula: see text] and correct the measurement parameters of the next step according to the previous measurement results. The method can update the measurement parameters in real time and perform automatic measurements. At the same time, this method greatly reduces the measurement time. The experimental results show that the method is suitable for the measurement of the self-diffusion coefficient D0 and longitudinal relaxation time T1, which are frequently used in NMR measurements.
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