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Updated: Jul 25, 2025

Cross-Modal Multivariate Pattern Analysis
Published on: November 9, 2011
MultiVI: deep generative model for the integration of multimodal data
Tal Ashuach1,2, Mariano I Gabitto3,4,5, Rohan V Koodli2
1Center for Computational Biology, University of California, Berkeley, CA, USA.
Abstract:
Jointly profiling the transcriptome, chromatin accessibility and other molecular properties of single cells offers a powerful way to study cellular diversity. Here we present MultiVI, a probabilistic model to analyze such multiomic data and leverage it to enhance single-modality datasets. MultiVI creates a joint representation that allows an analysis of all modalities included in the multiomic input data, even for cells for which one or more modalities are missing. It is available at scvi-tools.org .
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