Dissipation patterns, residue analysis, and risk evaluation of hexaflumuron in turnip and cauliflower under Chinese...

Hexaflumuron has been globally registered over 2 decades to control the pests in brassicaceous vegetables, while data on its dissipation and residues in turnip and cauliflower is scarce. Herein, field trials were carried out at six representative experimental sites to study the dissipation behaviors and terminal residues of hexaflumuron in turnip and cauliflower. The residual amounts of hexaflumuron were extracted using a modified QuEChERS and analyzed with liquid chromatography-tandem mass spectrometry (HPLC-MS/MS), the chronic dietary risk to Chinese populations was evaluated, and the maximum residue limit (MRL) in cauliflower, turnip tubers, and turnip leaves was calculated by the OECD MRL calculator. The single first-order kinetics model was the best-fitted kinetics model for hexaflumuron dissipation in cauliflower. The indeterminate order rate equation and first-order multi-compartment kinetic model were the best formulae for hexaflumuron dissipation in turnip leaves. The half-lives of hexaflumuron ranged from 0.686 to 1.35 and 2.41 to 6.71 days in cauliflower and turnip leaves, respectively. The terminal residues of hexaflumuron in turnip leaves of 0.321-9.59 mg/kg were much higher than in turnip tubers of < 0.01-0.708 mg/kg and cauliflower of < 0.01-1.49 mg/kg at sampling intervals of 0, 5, 7, and 10 days. The chronic dietary risk of hexaflumuron in the preharvest interval of 7 days was lower than 100% and much higher than 0.01%, indicating acceptable but nonnegligible health hazards for Chinese consumers. Therefore, MRL values of hexaflumuron were proposed as 2, 0.8, and 10 mg/kg in cauliflower, turnip tubers, and turnip leaves, respectively.