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Anal and perianal malignancies.

D E Waugh

    The Surgical Clinics of North America
    |August 1, 1986
    PubMed
    Summary

    Perianal carcinomas are treated like other skin cancers. Anal canal squamous cell carcinomas under 2 cm can be locally excised; larger tumors often require radiation or chemoradiation, potentially followed by surgery.

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    Area of Science:

    • Oncology
    • Surgical Oncology
    • Radiation Oncology

    Background:

    • Perianal and anal canal carcinomas are distinct entities requiring different management strategies.
    • Perianal malignancies are typically managed similarly to cutaneous skin cancers.
    • Anal canal carcinomas necessitate specific oncological treatment protocols.

    Purpose of the Study:

    • To delineate the management differences between perianal and anal canal carcinomas.
    • To outline current treatment guidelines for squamous cell carcinomas of the anal canal.
    • To emphasize the importance of accurate tumor classification for effective treatment planning.

    Main Methods:

    • Distinguishing perianal carcinomas from anal canal carcinomas based on anatomical location (anal verge).
    • Reviewing treatment modalities for skin malignancies applied to perianal cancers.
    • Evaluating treatment options for squamous cell carcinomas of the anal canal, including local excision, radiation therapy, and chemotherapy.

    Main Results:

    • Perianal malignancies are managed as skin cancers.
    • Squamous cell carcinomas of the anal canal < 2 cm diameter are amenable to local excision.
    • Larger epidermoid anal canal carcinomas are treated with radiation or chemoradiation, with surgery for residual disease.

    Conclusions:

    • Accurate segregation of perianal and anal canal carcinomas is crucial for appropriate treatment.
    • Local excision is a viable option for small squamous cell anal canal carcinomas.
    • Multimodal therapy, including radiation and chemotherapy, is standard for advanced anal canal carcinomas.

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