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Updated: Jul 25, 2025

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
Predicting In-Hospital Mortality During the COVID-19 Pandemic in Patients with Heart Failure: A Single-Center
Antonio D'Amore1, Gaetano D'Onofrio1, Andrea Fidecicchi1
1A.O.R.N. "Antonio Cardarelli", Naples, Italy.
Insights
This study examined if COVID-19 pandemic exposure increased heart failure in-hospital mortality. While not statistically significant, findings suggest other factors influence patient death rates during the pandemic.
Area of Science:
- Public Health
- Epidemiology
- Cardiology
Background:
- The COVID-19 pandemic presented unprecedented challenges to healthcare systems globally.
- Understanding its impact on vulnerable patient populations, such as those with heart failure, is critical.
- Previous research has explored various pandemic-related health outcomes.
Purpose of the Study:
- To investigate the association between COVID-19 pandemic exposure and in-hospital mortality among heart failure patients.
- To assess the likelihood of in-hospital death in this cohort during the pandemic period.
- To identify potential factors influencing mortality and areas for clinical intervention.
Main Methods:
- Retrospective analysis of patient data.
- Inclusion of individuals hospitalized for heart failure between 2019 and 2020.
- Assessment of in-hospital mortality rates.
Main Results:
- A positive association between COVID-19 pandemic exposure and increased in-hospital mortality for heart failure was observed.
- This association did not reach statistical significance.
- The findings suggest that other unmeasured factors may play a role in mortality outcomes.
Conclusions:
- The study highlights the need for further investigation into the complex relationship between pandemics and cardiovascular mortality.
- While not statistically significant, the trend warrants attention and potential for future research.
- Identifying influencing factors is key to improving patient care and interventions during health crises.
Abstract:
The aim of this study was to investigate whether exposure to the pandemic was associated with increased in-hospital mortality for health failure. We collected data from patients hospitalized between 2019 and 2020 and we assessed the likelihood of in-hospital death. Although the positive association of exposure to the COVID period with an increased in-hospital mortality is not statistically significant, this may underscore other factors that may influence mortality. Our study was designed to contribute to a better understanding of the impact of the pandemic on in-hospital mortality and to identify potential areas for intervention in patient care.
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