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    Area of Science:

    • Biomedical optics
    • Medical imaging technology
    • Optical engineering

    Background:

    • Polarization artifacts are common in optical coherence tomography (OCT).
    • Modern OCT systems use polarized light, leading to signal loss when light polarization mismatches.
    • Cross-polarized light in OCT does not interfere, causing artifacts like signal absence.

    Purpose of the Study:

    • To present a technique for preventing polarization artifacts in OCT.
    • To ensure consistent OCT signal detection irrespective of sample polarization state.
    • To offer a cost-effective solution applicable to various OCT setups.

    Main Methods:

    • Partly depolarizing the light source at the interferometer entrance.
    • Implementing a simple and cost-effective technique.
    • Testing the method in a defined retarder and dura mater tissue.

    Main Results:

    • Achieved OCT signals independent of the sample's polarization state.
    • Demonstrated effective artifact prevention in controlled and biological samples.
    • Validated the technique's performance in birefringent tissues.

    Conclusions:

    • The presented technique effectively eliminates cross-polarization artifacts in OCT.
    • This simple method enhances OCT image reliability across different sample types.
    • The approach is broadly applicable to diverse OCT system designs.