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Related Experiment Videos

Cystic renal cell carcinoma.

D S Hartman, C J Davis, T Johns

    Urology
    |August 1, 1986
    PubMed
    Summary

    Cystic renal cell carcinoma, a fluid-filled kidney cancer, presents challenges in diagnosis. This review details its clinical, pathologic, and radiographic features to aid in differentiating it from other masses.

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    Area of Science:

    • Nephrology
    • Oncology
    • Radiology

    Background:

    • Cystic renal cell carcinoma (CRCC) constitutes approximately 15% of renal cell carcinoma cases.
    • CRCC presents as a fluid-filled renal mass, often mimicking benign conditions.
    • Radiographic and pathologic findings of CRCC can be less specific than solid renal masses.

    Purpose of the Study:

    • To review the clinical, pathologic, and radiographic features of CRCC.
    • To discuss the radiologic differential diagnosis of CRCC.
    • To enhance the differentiation of CRCC from other renal masses.

    Main Methods:

    • Review of clinical presentations of CRCC.
    • Analysis of pathologic mechanisms leading to cystic CRCC.
    • Examination of radiologic patterns associated with CRCC.

    Main Results:

    • Four main pathologic mechanisms result in CRCC: intrinsic multiloculated growth, intrinsic unilocular growth (cystadenocarcinoma), cystic necrosis, and origin from a preexisting simple cyst.
    • Three primary radiologic patterns are observed: unilocular cystic mass, multiloculated cystic mass, and discrete mural nodule within a cystic mass.
    • CRCC is often difficult to distinguish from non-neoplastic, benign neoplastic, and other malignant masses based on imaging alone.

    Conclusions:

    • Understanding the diverse presentations of CRCC is crucial for accurate diagnosis.
    • Radiologic interpretation requires careful consideration of CRCC's unique features.
    • Further refinement of diagnostic criteria may improve differentiation of CRCC.

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