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Updated: Jul 24, 2025

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
[Ten perspectives for research and innovation in cardiac amyloidosis]
Aldostefano Porcari1, Alberto Aimo2, Giuseppe Vergaro2
1S.C. Cardiologia, Dipartimento Cardiotoracovascolare, Centro per la Diagnosi e Cura delle Cardiomiopatie, Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI) e Università degli Studi di Trieste, Trieste - European Reference Network for rare, low prevalence, or complex diseases of the Heart (ERN GUARD-Heart) - National Amyloidosis Centre, Division of Medicine, University College London, Royal Free Campus, Londra, UK.
Abstract:
Our view of amyloidosis has changed deeply over the last 10 years following major advances in diagnosis and treatment options, especially in cardiac amyloidosis. This intrinsically heterogeneous disease requires the interaction among experts of different specialties and subspecialties. Suspicion of disease, timely recognition and confirmation of final diagnosis, prognostic stratification, clinical management and therapeutic strategies represent essential steps to be taken. The Italian Network for Cardiac Amyloidosis is able to deal with the challenges of this condition and orient clinical management of patients at either national or local level. The present review article aims to provide potential research questions on cardiac amyloidosis that have not been investigated yet and that the Italian Network might explore in the near future.
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Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...

