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A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
Published on: October 13, 2023
FAIR-Checker: supporting digital resource findability and reuse with Knowledge Graphs and Semantic Web standards
Alban Gaignard1, Thomas Rosnet2,3, Frédéric De Lamotte4
1Nantes Université, CNRS, INSERM, l'institut du thorax, F-44000, Nantes, France. alban.gaignard@univ-nantes.fr.
Abstract:
The current rise of Open Science and Reproducibility in the Life Sciences requires the creation of rich, machine-actionable metadata in order to better share and reuse biological digital resources such as datasets, bioinformatics tools, training materials, etc. For this purpose, FAIR principles have been defined for both data and metadata and adopted by large communities, leading to the definition of specific metrics. However, automatic FAIRness assessment is still difficult because computational evaluations frequently require technical expertise and can be time-consuming. As a first step to address these issues, we propose FAIR-Checker, a web-based tool to assess the FAIRness of metadata presented by digital resources. FAIR-Checker offers two main facets: a "Check" module providing a thorough metadata evaluation and recommendations, and an "Inspect" module which assists users in improving metadata quality and therefore the FAIRness of their resource. FAIR-Checker leverages Semantic Web standards and technologies such as SPARQL queries and SHACL constraints to automatically assess FAIR metrics. Users are notified of missing, necessary, or recommended metadata for various resource categories. We evaluate FAIR-Checker in the context of improving the FAIRification of individual resources, through better metadata, as well as analyzing the FAIRness of more than 25 thousand bioinformatics software descriptions.
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