Comparison of four commercial dose calculation algorithms in different evaluation tests.

Area of Science:

• Medical Physics
• Radiation Oncology
• Computational Dosimetry

Background:

• Accurate dose calculation is essential for effective radiation therapy.
• Four dose calculation algorithms (AAA, AXB, CCC, MC) are used in Varian Eclipse and RayStation Treatment Planning Systems (TPSs).

Purpose of the Study:

• To evaluate and compare the dosimetric accuracy of four dose calculation algorithms.
• Assess accuracy in homogeneous and heterogeneous media, VMAT plans, and surface/buildup regions.

Main Methods:

• Algorithms assessed in homogeneous (IAEA-TECDOCE 1540) and heterogeneous (IAEA-TECDOC 1583) media.
• Dosimetric accuracy evaluated for VMAT plans based on AAPM TG-119 test cases.
• Accuracy in surface and buildup regions analyzed.

Main Results:

• All algorithms showed dose deviations within 5% in homogeneous media (pass rates >95%).
• Heterogeneous media tests showed high pass rates, with AXB and MC demonstrating lower discrepancies, especially in superficial regions.
• Gamma index pass rates (3%/3mm) for TG119 tests exceeded 97% for all algorithms.

Conclusions:

• Dose-to-medium algorithms (AXB, MC) generally exhibit better dosimetric accuracy than dose-to-water algorithms (AAA, CCC).
• This finding is crucial for optimizing treatment planning systems and improving radiation therapy outcomes.