Related Experiment Video
Updated: Jul 24, 2025

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
Where does capsule endoscopy fit in the diagnostic algorithm of small bowel intussusception?
Stefania Chetcuti Zammit1, Aman Yadav2, Deirdre McNamara2
1Division of Gastroenterology, Mater Dei Hospital, Msida MSD 2090, Malta.
Small bowel capsule endoscopy (SBCE) complements radiology for intussusception diagnosis. This safe, non-invasive test helps avoid unnecessary surgeries and repeat imaging when initial results are negative.
Area of Science:
- Gastroenterology
- Diagnostic Imaging
- Endoscopy
Background:
- Small bowel (SB) intussusception diagnosis lacks standardized approaches.
- Small bowel capsule endoscopy (SBCE) role in investigating SB intussusception requires clarification.
Purpose of the Study:
- To evaluate the utility of SBCE in diagnosing small bowel intussusception.
- To understand the diagnostic yield of SBCE compared to radiological investigations.
Main Methods:
- Retrospective multi-center study including 95 patients with intussusception identified on SBCE or prior radiological imaging.
- Analysis of SBCE findings in conjunction with radiological investigations (CT, etc.).
Main Results:
- SBCE identified abnormalities explaining intussusception in 22.5% of patients.
- In 42.2% of cases with radiological intussusception, SBCE was normal.
- Repeat radiology after negative SBCE rarely yielded positive findings (14.1%).
- SBCE identified masses in 4.2% of patients, leading to surgery.
Conclusions:
- SBCE serves as a valuable adjunct to radiology for small bowel intussusception.
- SBCE can minimize unnecessary surgical interventions.
- Further radiological investigations after a negative SBCE for intussusception are generally not productive.
Related Concept Videos
Endoscopic Procedures III: Video Capsule Endoscopy
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Endoscopic Procedures II: Colonoscopy
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...

