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Updated: Jul 24, 2025

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Single Port Donor Nephrectomy
Published on: March 12, 2011
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Transperitoneal Versus Retroperitoneal Single-port Robotic-assisted Partial Nephrectomy: An Analysis from the Single
Jordan M Rich1, Kennedy E Okhawere1, Charles Nguyen1
1Icahn School of Medicine at Mount Sinai, New York, NY, USA.
European Urology Focus
|July 2, 2023
Summary
Single-port (SP) robotic-assisted partial nephrectomy (RAPN) using either the transperitoneal (TP) or retroperitoneal (RP) approach yields comparable outcomes. Surgeons can select the TP or RP approach for SP RAPN based on patient and tumor characteristics for satisfactory results.
Area of Science:
- Urology
- Minimally Invasive Surgery
- Robotic Surgery
Background:
- Single-port (SP) robotic-assisted partial nephrectomy (RAPN) is an emerging technique for kidney tumor management.
- The transperitoneal (TP) and retroperitoneal (RP) approaches are utilized for SP RAPN, but comparative outcome data are limited.
Purpose of the Study:
- To compare the perioperative and postoperative outcomes of the TP versus RP approaches in SP RAPN.
Main Methods:
- A retrospective cohort study analyzed data from the Single Port Advanced Research Consortium (SPARC) database (2019-2022).
- 219 patients undergoing SP RAPN for renal masses were compared between TP and RP groups.
- Statistical analyses included chi-squared test, Fisher exact test, Mann-Whitney U test, and Student t test.
Main Results:
- No significant differences were observed in ischemia time, operative time, estimated blood loss, length of stay, or overall/major complication rates between TP and RP groups.
- Posterior tumors were more common in the RP group (p < 0.001), but other baseline characteristics were comparable.
- Positive surgical margin rates and estimated glomerular filtration rate (eGFR) changes at 6 months were similar for both approaches.
Conclusions:
- Both the TP and RP approaches are viable options for SP RAPN.
- Patient and tumor characteristics should guide the selection of the TP or RP approach to ensure satisfactory surgical outcomes.

