An Ultrasensitive Plasmonic Sensor Based on 2D Ferroelectric Bi₂ O₂ Se

Area of Science:

• Materials Science
• Biotechnology
• Nanotechnology

Background:

• Plasmonic biosensing offers label-free detection of biomolecular interactions.
• Current limitations include achieving high sensitivity and low detection limits for biomolecules at low concentrations.

Purpose of the Study:

• To enhance sensitivity in plasmonic biosensor design using 2D ferroelectric materials.
• To develop an ultrasensitive biosensor for protein detection.

Main Methods:

• Fabrication of a plasmonic sensor utilizing Bismuth Oxy-Selenide (Bi2O2Se) nanosheets, a 2D ferroelectric material.
• Characterization of the sensor's performance through surface charge density imaging.
• Detection of bovine serum albumin (BSA) as a model protein molecule.

Main Results:

• Achieved an ultra-low detection limit of 1 femtomolar (fM) for bovine serum albumin (BSA).
• Demonstrated the effectiveness of 2D ferroelectric materials in improving biosensor sensitivity.

Conclusions:

• 2D ferroelectric materials show significant potential for advancing biosensor technology.
• Bi2O2Se nanosheets can serve as key components in future ultrasensitive biomaterial architectures.