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Halogen halos: Report of an early histopathologic finding in iododerma
Avi Bitterman1, Melissa Peri Zundell1, Corinna Psomadakis2
1Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Abstract:
Iododerma is a rare cutaneous eruption that manifests after exposure to iodine-containing compounds, with few cases reported in the literature. Previous reports of this halogenoderma have described acellular halos simulating cryptococcus on histopathological examination but there is a paucity of reports of biopsies taken early in the disease course. We present a case of a 78-year-old patient who developed a papular eruption after receiving iodinated contrast. A skin biopsy taken within 24 h of the eruption showed a neutrophilic infiltrate with cryptococcal-like acellular haloed structures, indicating that the diagnostic finding may be found early in the disease course.
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