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Pathophysiological Link Between Chronic Rhinosinusitis and Ear Disease.

Christian Calvo-Henriquez1,2, Eugenio Di Corso3, Isam Alobid4

  • 1Rhinology Study Group of the Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), Paris, France. christian.calvo.henriquez@gmail.com.

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PubMed
Summary

Chronic rhinosinusitis (CRS) is linked to frequent ear symptoms, particularly Eustachian tube dysfunction. Treating CRS often improves these ear conditions, with emerging evidence for biologic therapies in specific cases.

Keywords:
CRSwNPCholesteatomaChronic otitis mediaChronic rhinosinusitis (CRS)Eosinophilic otitisHearing lossMonoclonal antibodies

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Area of Science:

  • Otolaryngology
  • Immunology

Background:

  • Chronic rhinosinusitis (CRS) frequently presents with otologic symptoms in clinical practice.
  • Understanding the link between CRS and ear conditions is crucial for comprehensive patient care.

Purpose of the Study:

  • To review recent literature (last 5 years) on the relationship between CRS and ear illnesses.
  • To synthesize evidence regarding the prevalence and impact of otologic symptoms in CRS patients.

Main Methods:

  • Literature review of studies published within the last five years.
  • Analysis of evidence linking CRS to various otologic conditions.

Main Results:

  • Otologic symptoms affect up to 87% of CRS patients, commonly Eustachian tube dysfunction.
  • Eustachian tube function often improves after CRS treatment.
  • Preliminary data suggest potential roles for CRS in cholesteatoma, chronic otitis media, and sensorineural hearing loss, with eosinophilic otitis media responding to biologics.

Conclusions:

  • Eustachian tube dysfunction is strongly associated with CRS and improves with treatment.
  • Further research is needed to confirm the role of CRS in other otologic conditions like cholesteatoma and chronic otitis media.
  • Biologic therapies show promise for specific CRS-related ear conditions such as eosinophilic otitis media.