Related Experiment Video

Updated: Jul 24, 2025

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice
14:10

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice

Published on: July 29, 2022

5.4K

Mycotic Pseudoaneurysm of Thoracic Aortic Caused by Salmonella Paratyphi A: A Case Report

Ying Han1, Yue Zhang1, Gege Gong2

  • 1Department of Pain Management, The Affiliated Hospital of Southwest Medical University, Luzhou, People's Republic of China.

Infection and Drug Resistance
|July 3, 2023
PubMed
Abstract

Insights

A rare case of thoracic aortic pseudoaneurysm caused by Salmonella paratyphi A infection was successfully treated. This infectious pseudoaneurysm was managed with endovascular stent-graft treatment and antibiotics.

Area of Science:

  • Infectious diseases
  • Cardiovascular surgery
  • Medical microbiology

Background:

  • Mycotic pseudoaneurysm, or infectious pseudoaneurysm, is a serious condition with high mortality.
  • Salmonella species are common causes, but Salmonella paratyphi A is an extremely rare etiology.
  • Endovascular therapy is a recognized feasible treatment option.

Observation:

  • A 63-year-old female patient with diabetes presented with fever, abdominal pain, and low back pain.
  • She was diagnosed with a thoracic aortic pseudoaneurysm attributed to Salmonella paratyphi A infection.
  • The patient underwent successful treatment with endovascular stent-graft placement and antibiotics.

Findings:

  • Salmonella paratyphi A can cause mycotic pseudoaneurysms, even in the thoracic aorta.
  • Endovascular stent-graft treatment, combined with antibiotics, proved effective in this case.
  • This approach offers an alternative for patients unsuitable for open surgery.

Implications:

  • Highlights the potential of Salmonella paratyphi A to cause severe vascular infections.
  • Demonstrates the efficacy of endovascular stent-graft repair for mycotic thoracic aortic pseudoaneurysms.
  • Supports endovascular therapy as a viable alternative to open surgery in select patients.
Keywords:
antibioticbloodstream infectionendovascular treatmentinfectious pseudoaneurysm

More Related Videos

Chronic Salmonella Infection Induced Intestinal Fibrosis08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

7.2K
Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm00:08

Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm

Published on: August 24, 2019

7.7K

Related Concept Videos

Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
15
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
10
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
10