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Related Experiment Video

Updated: Jul 24, 2025

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage

Published on: February 10, 2023

Polymorphisms and NIHL: a systematic review and meta-analyses.

Lu Wang¹, HanYu Wang¹, Feng Xiang¹

¹Clinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.

Frontiers in Cellular Neuroscience

|July 3, 2023

Summary

This summary is machine-generated.

This meta-analysis identified specific gene polymorphisms associated with noise-induced hearing loss (NIHL) susceptibility. These findings are crucial for developing risk prediction systems to prevent NIHL in high-risk populations.

Keywords:

CAT EYA4 GRHL2 HSP70 meta-analysis noise induced hearing loss polymorphism

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Last Updated: Jul 24, 2025

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Published on: February 10, 2023

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Area of Science:

Genetics
Public Health
Audiology

Background:

Noise-induced hearing loss (NIHL) is a significant global health issue influenced by noise exposure and genetic factors.
Identifying genetic polymorphisms linked to individual susceptibility is key to understanding and preventing NIHL.
Previous research has explored various genetic factors, necessitating a comprehensive analysis.

Conclusions:

Specific gene polymorphisms (GRHL2, CAT, EYA4, HSP70) are significantly associated with NIHL susceptibility.
These identified polymorphisms hold potential value for NIHL risk prediction and prevention, especially in high-risk groups.
This research represents a crucial step towards establishing a population-based risk prediction system for NIHL.