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Acupuncture for premature ejaculation: a systematic review and meta-analysis.
Hui Zhang1, Elena Colonnello1,2, Andrea Sansone1
1Department of Experimental Medicine, University of Rome Tor Vergata, Rome 00133, Italy.
Sexual Medicine
|July 3, 2023
Summary
Acupuncture shows promise for treating premature ejaculation (PE), significantly improving some subjective measures. However, low-quality evidence necessitates caution and further research for definitive conclusions.
Area of Science:
- Integrative and Complementary Medicine
- Men's Health
- Urology
Background:
- Premature ejaculation (PE) is a common condition affecting men's sexual health.
- Acupuncture is a frequently utilized treatment for PE, yet its efficacy is debated.
Purpose of the Study:
- To systematically evaluate the efficacy and safety of acupuncture for treating premature ejaculation (PE).
- To synthesize findings from randomized controlled trials (RCTs) comparing acupuncture with other treatments or sham acupuncture.
Main Methods:
- A comprehensive search of 11 major English and Chinese databases was conducted for RCTs on acupuncture for PE.
- The GRADEpro tool was used to assess the quality of evidence across the included studies.
- Outcome measures included intravaginal ejaculation latency time (IELT), PE diagnostic tools (PEDT, CIPE-5), and treatment success rates.
Main Results:
- Acupuncture significantly improved IELT and PEDT scores compared to sham acupuncture.
- Compared to other treatments, acupuncture combined with other therapies improved IELT, CIPE-5 scores, and treatment success rates.
- Acupuncture was associated with lower CIPE-5 scores compared to selective serotonin reuptake inhibitors, but evidence quality was low.
Conclusions:
- Acupuncture demonstrates a significant effect on several subjective parameters of PE, particularly when used adjunctively.
- The current evidence base is limited by the low quality of included RCTs.
- Larger, well-designed RCTs are required to confirm the therapeutic role of acupuncture in PE management.

