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Production of toxin in strains previously classified as Pasteurella multocida
Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Section B, Microbiology
|June 1, 1986
Abstract:
169 strains of P. multocida ssp. multocida, 24 strains of P. multocida ssp. septica, 22 strains of P. multocida ssp. gallicida, and 8 strains of P. avium and P. canis, respectively, were tested for toxin production in EBL-cell culture assay. Toxin production was only demonstrated in strains belonging to P. multocida ssp. multocida. Toxigenic strains were derived from pigs, calves, cats, dogs, rabbits and turkeys.
Insights
Toxin production was identified only in P. multocida ssp. multocida strains. These toxigenic strains were isolated from various animal species, including pigs, calves, cats, dogs, rabbits, and turkeys.
Area of Science:
- Veterinary Microbiology
- Bacterial Pathogenesis
Background:
- * Pasteurella multocida is a significant bacterial pathogen in veterinary medicine.
- * Different subspecies and species of Pasteurella are recognized, with varying pathogenic potential.
- * Toxin production is a key virulence factor in many bacterial infections.
Purpose of the Study:
- * To investigate toxin production capabilities across various Pasteurella multocida subspecies and related species.
- * To identify which Pasteurella strains are capable of producing toxins.
- * To determine the animal origins of toxigenic Pasteurella strains.
Main Methods:
- * A collection of 169 P. multocida ssp. multocida, 24 P. multocida ssp. septica, 22 P. multocida ssp. gallicida, and 8 P. avium/P. canis strains were analyzed.
- * Toxin production was assessed using an EBL-cell culture assay.
Main Results:
- * Toxin production was exclusively detected in strains belonging to P. multocida ssp. multocida.
- * Toxigenic strains were isolated from a diverse range of animals: pigs, calves, cats, dogs, rabbits, and turkeys.
Conclusions:
- * P. multocida ssp. multocida is the primary subspecies associated with toxin production among the tested Pasteurella strains.
- * The presence of toxigenic P. multocida ssp. multocida in multiple animal hosts highlights its broad host range and potential for widespread disease.