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Published on: May 18, 2020
Atypical hyperplasia of the breast: Clinical cases and management strategies
Suneela Vegunta1, Dawn M Mussallem2, Aparna S Kaur3
1Assistant Professor of Medicine; Vice-Chair, Division of Women's Health Internal Medicine, Mayo Clinic, Scottsdale, AZ vegunta.suneela@mayo.edu.
Abstract:
Atypical hyperplasia of the breast is a histopathologic lesion identified incidentally on image-guided breast biopsy. It is associated with a substantial increase in lifetime risk for breast cancer. Clinicians should counsel women with atypical hyperplasia regarding risk-reducing strategies, which include preventive endocrine therapy options, enhanced surveillance imaging, and lifestyle modifications. In this review, we describe 5 different but common clinical case scenarios for atypical hyperplasia of the breast and review management strategies for each scenario.

