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Published on: April 17, 2021
Assessment of misdiagnosis in small animal intensive care patients using the Modified Goldman criteria
Sanne Hugen1, Nynke Ankringa2, Joris Henricus Robben1
1Department of Clinical Sciences of Companion Animals, Utrecht University, Utrecht, The Netherlands.
Abstract:
The postmortem examination can be used as a means of quality control for clinical diagnoses. A retrospective study on 300 dogs and cats that had been admitted to a small animal intensive care unit was performed comparing the clinical and postmortem findings, using the Modified Goldman criteria. All patient files were reevaluated for clinical diagnoses and all postmortem material was reevaluated for pathological diagnoses. After this, the Modified Goldman criteria were applied to score the discrepancies between them, and factors associated with the occurrence of an undiagnosed major unexpected finding were analyzed. The postmortem examination revealed additional findings in 65% of the cases. Major discrepancies, defined as those affecting treatment and possibly outcome of the patient, were present in 21.3% of the cases. The most frequently missed diagnoses detected at necropsy were pneumonia of various etiologies, meningitis/meningoencephalitis, myocarditis and generalized vasculitis. A shorter ICU stay was associated with increased odds of a major discrepancy. Conditions affecting the urinary or gastrointestinal system were negatively associated with major discrepancy.
Insights
Postmortem examinations revealed significant discrepancies in 21.3% of clinical diagnoses for pets in intensive care units (ICUs). This quality control highlights common missed diagnoses like pneumonia and meningitis, impacting patient outcomes.
Area of Science:
- Veterinary Pathology
- Comparative Pathology
- Diagnostic Accuracy
Background:
- Postmortem examinations serve as a crucial quality control measure for clinical diagnoses in veterinary medicine.
- Accurate clinical diagnoses are essential for effective treatment and improved patient outcomes in small animal intensive care units (ICUs).
Purpose of the Study:
- To evaluate the diagnostic accuracy of clinical assessments in critically ill small animals by comparing them with postmortem findings.
- To identify the frequency and nature of discrepancies between clinical and pathological diagnoses.
- To analyze factors associated with undiagnosed major findings.
Main Methods:
- Retrospective study of 300 dogs and cats admitted to a small animal ICU.
- Comparison of clinical diagnoses with postmortem findings using the Modified Goldman criteria.
- Analysis of patient files and postmortem material for diagnostic discrepancies.
Main Results:
- Postmortem examination revealed additional findings in 65% of cases.
- Major discrepancies, impacting treatment and outcome, were present in 21.3% of cases.
- Commonly missed diagnoses included pneumonia, meningitis/meningoencephalitis, myocarditis, and vasculitis.
- Shorter ICU stays correlated with higher odds of major discrepancies.
Conclusions:
- Significant discrepancies exist between clinical diagnoses and postmortem findings in small animal ICUs.
- Postmortem examinations are vital for identifying diagnostic errors and improving the quality of veterinary care.
- Missed diagnoses in critical care settings can affect patient outcomes, underscoring the need for thorough diagnostic evaluation.
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