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Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

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[Modern methods for determining the positive surgical margin during radical prostatectomy].

I S Byadretdinov^1,2, S V Kotov^1,2

¹Pirogov Russian National Research Medical University, Moscow, Russia.

Urologiia (Moscow, Russia : 1999)

|July 4, 2023

Summary

Identifying predictors of biochemical recurrence (BCR) is crucial for effective prostate cancer treatment. Positive surgical margins after radical prostatectomy are a key risk factor for BCR.

Keywords:

method for determining the surgical margin prostate cancer prostatectomy surgical margin

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Published on: October 10, 2019

Area of Science:

Urology
Oncology
Medical Technology

Background:

Biochemical recurrence (BCR) following radical prostatectomy for prostate cancer is a significant concern.
Positive surgical margins are an independent predictor of BCR.
Effective treatment necessitates accurate intraoperative assessment of surgical margins.

Approach:

A systematic review of PubMed and Web of Science databases was conducted.
Articles published between 1995 and 2020 were included.
Keywords: prostate cancer, surgical margin, radical prostatectomy, biochemical recurrence, methods for determining the surgical margin.

Key Points:

Several technologies are under development for real-time surgical margin assessment.
These include aminolevulinic acid, optical coherence tomography, optical spectroscopy, and confocal laser microscopy.
3D augmented reality, 3D modeling, and frozen sample analysis are also being investigated.

Conclusions:

Accurate intraoperative determination of surgical margins can improve prostate cancer treatment outcomes.
Emerging technologies offer promising avenues for enhancing surgical margin evaluation during radical prostatectomy.
Further research and validation of these methods are essential.