Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

81
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
81
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

300
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
300
Group Design02:01

Group Design

9.0K
The most basic experimental design involves two groups: the experimental group and the control group. The two groups are designed to be the same except for one difference— experimental manipulation. The experimental group gets the experimental manipulation—that is, the treatment or variable being tested—and the control group does not. Since experimental manipulation is the only difference between the experimental and control groups, we can be sure that any differences between...
9.0K
Randomized Experiments01:13

Randomized Experiments

7.0K
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
7.0K
Random Variables01:09

Random Variables

12.4K
A random variable is a single numerical value that indicates the outcome of a procedure. The concept of random variables is fundamental to the probability theory and was introduced by a Russian mathematician, Pafnuty Chebyshev, in the mid-nineteenth century.
Uppercase letters such as X or Y denote a random variable. Lowercase letters like x or y denote the value of a random variable. If X is a random variable, then X is written in words, and x is given as a number.
For example, let X = the...
12.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Matrix Commitment-based Ownership Verification for Distributed Machine Learning.

IEEE transactions on pattern analysis and machine intelligence·2026
Same author

PromptSED: An evolving topic-enhanced prompting framework for incremental social event detection.

Neural networks : the official journal of the International Neural Network Society·2025
Same author

Decoupled GNNs based on multi-view contrastive learning for scRNA-seq data clustering.

Briefings in bioinformatics·2025
Same author

Fuzzy Adaptive Knowledge-Based Inference Neural Networks: Design and Analysis.

IEEE transactions on cybernetics·2024
Same author

Statistical and clustering analysis of attributes of Bitcoin backbone nodes.

PloS one·2023
Same author

Decentralized Policy-Hidden Fine-Grained Redaction in Blockchain-Based IoT Systems.

Sensors (Basel, Switzerland)·2023
Same journal

Granular Ball-Based Noise-Resistant Fuzzy Multineighborhood Feature Selection via Label Enhancement and Feature Graph.

IEEE transactions on neural networks and learning systems·2026
Same journal

Fighting Evolving Spam With ARTMAP Models: A Noise-Resilient Online Detection Framework.

IEEE transactions on neural networks and learning systems·2026
Same journal

HyperSAT: Unsupervised Hypergraph Neural Networks for Weighted MaxSAT Problems.

IEEE transactions on neural networks and learning systems·2026
Same journal

Negation of Basic Belief Assignment in Multisource Information Fusion on Dempster-Shafer Theory With Applications in Pattern Classification.

IEEE transactions on neural networks and learning systems·2026
Same journal

Intervention Feasible Region and Driver Risk Capacity Aware Human-Machine Collaborative Safe Trajectory Planning.

IEEE transactions on neural networks and learning systems·2026
Same journal

A Unified Differential Denoising Learning Framework With a Pre-Trained Model and Fuzzy Graph Networks for Drug-Drug Interaction Prediction.

IEEE transactions on neural networks and learning systems·2026
See all related articles

Related Experiment Video

Updated: Jul 24, 2025

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

10.4K

Random Polynomial Neural Networks: Analysis and Design.

Wei Huang, Yueyue Xiao, Sung-Kwun Oh

    IEEE Transactions on Neural Networks and Learning Systems
    |July 4, 2023
    PubMed
    Summary
    This summary is machine-generated.

    Random polynomial neural networks (RPNNs) leverage random forest (RF) architecture for improved modeling. These RPNNs demonstrate superior performance in capturing complex nonlinear relationships compared to traditional methods.

    More Related Videos

    Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions
    07:38

    Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions

    Published on: June 7, 2024

    1.6K
    Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits
    10:32

    Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits

    Published on: April 15, 2015

    8.5K

    Related Experiment Videos

    Last Updated: Jul 24, 2025

    Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
    11:18

    Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

    Published on: March 2, 2015

    10.4K
    Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions
    07:38

    Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions

    Published on: June 7, 2024

    1.6K
    Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits
    10:32

    Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits

    Published on: April 15, 2015

    8.5K

    Area of Science:

    • Artificial Intelligence
    • Machine Learning
    • Computational Neuroscience

    Background:

    • Polynomial Neural Networks (PNNs) are effective for modeling complex nonlinear systems.
    • Traditional PNNs utilize polynomial neurons (PNs) that can be sensitive to outliers and prone to overfitting.
    • Random Forests (RFs) offer ensemble learning benefits, including robustness and variable importance estimation.

    Purpose of the Study:

    • To introduce Random Polynomial Neural Networks (RPNNs) by integrating RF architecture into PNNs.
    • To enhance the robustness and accuracy of nonlinear system modeling.
    • To address limitations of conventional PNNs, such as outlier sensitivity and overfitting.

    Main Methods:

    • Developed Random Polynomial Neurons (RPNs) based on RF architecture, generalizing PNs.
    • Utilized polynomial target variables for prediction in RPNs, deviating from direct target variable use in decision trees.
    • Employed the correlation coefficient for RPN selection within layers, instead of conventional performance indices.
    • Optimized RPNN parameters using Particle Swarm Optimization (PSO).

    Main Results:

    • RPNs demonstrated insensitivity to outliers.
    • RPNs provided insights into input variable importance post-training.
    • The RF structure in RPNs effectively alleviated the overfitting problem.
    • RPNNs combined the high accuracy of RF ensemble learning with PNN's ability to model high-order nonlinear relations.
    • Experimental results on benchmark datasets showed RPNNs outperformed existing state-of-the-art models.

    Conclusions:

    • RPNNs offer a robust and accurate approach for modeling complex nonlinear systems.
    • The integration of RF and PNN architectures yields significant advantages over conventional methods.
    • RPNNs represent a promising advancement in machine learning for complex system modeling.