[Skin lesions associated with invasive candidiasis in a neutropenic patient with acute myeloid leukemia]
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Ignacio Martín Santarelli1, Agustín Brest2, Pablo Jorge Juri3
1Hospital de Clínicas "José de San Martín", Universidad de Buenos Aires. isantarelli@fmed.uba.ar.
Abstract:
A 51-year-old male with profound and prolonged neutropenia 12 days after receiving chemotherapy for an acute myeloid leukemia developed a nodular, erythematous lesion with a necrotic center on the base of the neck, associated with fever, chills, and myalgia. An invasive fungal infection was diagnosed after growth of Candia tropicalis in blood cultures. He evolved with multiple reddish papular lesions concentrated mainly on the trunk, although they also spread to the extremities. The most common skin lesions of disseminated candidiasis are erythematous-violaceous papules with vesicular centers, which, in some cases, can progress to necrosis. Other forms of cutaneous presentation of invasive candidiasis are ecthyma gangrenosum-like lesions, hemorrhagic plaques or bullae, rash resembling folliculitis, and subcutaneous nodules.
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