[Chylous ascites in NSCLC: It is not always malignant]
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Updated: Jul 24, 2025
Author Spotlight: Establishing a Murine Non-Small Cell Lung Cancer Model for Developing Nanoformulations of Anticancer Drugs
Published on: May 10, 2024
Mark Uhlenbruch1, Marie-Kristin Bärmann1, Volker Bertram1
1Pneumologie, Florence-Nightingale-Krankenhaus, Düsseldorf, Deutschland.
Abstract:
The etiology of chylous ascites is multifactorial. Malignant diseases, cirrhosis, trauma, lymphomatic abnormalities and mycobacteriosis are the most common causes. In NSCLC, chylous ascites is observed with peritoneal metastasis or abdominal lymph node metastases.RET alterations occur in 1-2% of NSCLC patients and since recently they can be treated in a targeted fashion.Our case report shows that new targeted therapies revolutionize prognosis, but confront us with the challenge of new and partly unknown side effects.
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