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COVID-19 vaccine acceptance among people living with HIV: A systematic review and meta-analysis

Janet Yohannes Ejamo1, Gebrehiwot Lema Legese2, Yeabsira Aklilu Tesfaye2

  • 1Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, Wachemo University, Hossana, Ethiopia.

Tropical Medicine & International Health : TM & IH
|July 4, 2023
PubMed

Insights

COVID-19 vaccine acceptance is low among people living with HIV (PLHIV) globally. Targeted strategies are crucial to increase uptake of the coronavirus disease 2019 vaccine in this vulnerable population.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Immunology

Background:

  • People living with HIV (PLHIV) are a priority group for COVID-19 vaccination due to increased risk of severe illness.
  • Understanding COVID-19 vaccine acceptance among PLHIV is critical for effective public health interventions.

Purpose of the Study:

  • To assess the global acceptance rate of coronavirus disease 2019 (COVID-19) vaccines among adults living with HIV (PLHIV).
  • To identify factors associated with COVID-19 vaccine hesitancy in the PLHIV population.

Main Methods:

  • A systematic review and meta-analysis of studies published between January 2020 and September 2021.
  • Searched multiple databases (MEDLINE, PSYINFO, CINHAL, Scopus, EMBASE) and other sources.
  • Pooled COVID-19 vaccine acceptance rates and conducted subgroup analyses and narrative analysis of hesitancy factors.

Main Results:

  • The overall pooled COVID-19 vaccine acceptance rate among adult PLHIV was 62%.
  • Acceptance rates showed slight variations by income level of countries and year of study.
  • Key reasons for hesitancy included concerns about vaccine safety, efficacy, side effects, and distrust in information sources.

Conclusions:

  • COVID-19 vaccine acceptance among PLHIV is generally low, highlighting a significant public health challenge.
  • Collaborative efforts are essential to enhance vaccine confidence and uptake in this population.
Abstract

Keywords:
COVID-19HIVvaccine

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