Related Experiment Video
Updated: Jul 24, 2025

In Vitro Thrombosis Test for Ventricular Assist Devices
Published on: March 21, 2025
Construction and Validation of a Protocol Targeting Patients on Oral Anticoagulation with Warfarin
Hannah Cardoso Barbosa1, Heloisa de Carvalho Torres1, João Antônio de Queiroz Oliveira1
1Universidade Federal de Minas Gerais, Belo Horizonte, MG - Brasil.
Background:
Warfarin is an oral anticoagulant that is very useful in preventing thromboembolism, though it is considered a drug with a high risk of causing adverse events. Considering the practical challenges in controlling oral anticoagulation, the patients on warfarin could benefit from educational strategies aimed at behavioral changes, active participation in self-care, and adherence to drug therapy.
Objective:
The aim was to construct and validate the EmpoderACO protocol for behavioral changes in warfarin patients.
Methods:
The methodological steps were: definition of concepts and domains of self-care, identification of objectives, construction and selection of items, assessment of content validity, and pre-test in the target population.
Results:
Relevance, adequacy, clarity, and internal reliability of the instrument's items were assessed by a multidisciplinary judges committee (JC) through the E-surv web platform, obtaining an average agreement of ≥0.91. The understanding of the instrument measured by the target population revealed adequate clarity with a coefficient average of 0.96.
Conclusion:
EmpoderACO can aid in qualifying the communication process between medical professionals and patients, as well as in improving adherence to both treatment and clinical outcomes, and can be replicated in healthcare settings.
Related Concept Videos
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Venous Thrombosis III: Interprofessional Care
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Venous Thrombosis IV: Nursing Management
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Pre-Procedural Guidelines for Assessing Blood Pressure

