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Updated: Jul 24, 2025
Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
Published on: June 28, 2024
Periconceptional Folic Acid Only Versus Multiple Micronutrients Containing Folic Acid and Association with
Shuangbo Xia1,2, Yushan Du1,2, Ziyang Ren1,2
1Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
What Is Already Known About This Topic?:
Inconsistent results have been reported on the association between periconceptional folic acid only (FAO) or multiple micronutrients containing folic acid (MMFA) supplementation and the risk of gestational diabetes mellitus (GDM) in previous research.
What Is Added By This Report?:
In a prospective cohort study conducted among pregnant women in Haidian District, Beijing Municipality, it was observed that those who took MMFA demonstrated a higher likelihood of developing GDM in comparison to those who consumed FAO periconceptionally. Interestingly, the increased risk for GDM in pregnant women supplemented with MMFA compared to FAO was primarily due to changes in fasting plasma glucose.
What Are The Implications For Public Health Practice?:
It is highly recommended that women prioritize the use of FAO in order to yield potential benefits in the prevention of GDM.
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