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A case of adrenal myelolipoma complicated with Prader-Willi syndrome

Toru Inoue1,2, Masahiro Todaka2, Yuichi Nakazono3

  • 1Department of Urology, Faculty of Medicine Oita University Yufu-City Oita Japan.

IJU Case Reports
|July 5, 2023
PubMed

Insights

Prader-Willi syndrome (PWS) can be complicated by adrenal myelolipoma, a benign adrenal tumor. This report details the successful laparoscopic removal of an adrenal myelolipoma in a PWS patient.

Area of Science:

  • Endocrinology
  • Genetics
  • Surgical Oncology

Background:

  • Prader-Willi syndrome (PWS) is a complex genetic disorder affecting multiple systems.
  • Adrenal myelolipomas are rare, benign tumors typically asymptomatic.

Observation:

  • A 24-year-old male with PWS presented with an enlarged adrenal mass.
  • Imaging suggested an adrenal myelolipoma.
  • The patient underwent successful laparoscopic left adrenalectomy.

Findings:

  • Histopathology confirmed adrenal myelolipoma.
  • The patient experienced mild postoperative pulmonary atelectasis.
  • No recurrence was observed at 2-year follow-up.

Implications:

  • This is the first reported case of PWS associated with adrenal myelolipoma.
  • Laparoscopic adrenalectomy is a viable treatment option for adrenal myelolipoma in PWS patients.
  • Highlights the importance of monitoring for adrenal pathology in PWS.
Abstract

Keywords:
Prader‐Willi syndromeadrenal myelolipomaintellectual disabilitylaparoscopic adrenalectomyobesity

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