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Updated: Jul 24, 2025

A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats
Published on: November 11, 2013
Heroin-Induced Transverse Myelitis in a Chronic Heroin User: A Case Report
Mueez Hussain1, Drake Shafer2, Joseph Taylor1
1Internal Medicine, Southwest Healthcare MEC, Temecula, USA.
Abstract:
Transverse myelitis is a rare but documented sequela of heroin use. While the underlying etiology is not clearly elucidated, the prevailing pathophysiologic mechanism amongst existing literature suggests an immune-mediated hypersensitivity reaction due to heroin insufflation following a long period of abstinence. Outcomes vary among the limited reports, but prognosis tends to be poor due to an acute and rapidly progressive disease course. Here, we describe a case of extensive transverse myelitis in a chronic heroin user following heroin insufflation. This report hopes to provide greater insight into the underlying cause of this rare phenomenon due to our patient's discrepancy from the documented norm of heroin abstinence preceding disease onset.
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