Psychological stress, the central nervous system and arrhythmias
P D Lambiase1, S N Garfinkel2, P Taggart1
1UCL Institute of Cardiovascular Science & Barts Heart Centre, Rayne Institute, 5 University Street, London WC1E 6JF, UK.
Abstract:
This review highlights the links between psychological stress and the neurocircuitry of cardiac-brain interactions leading to arrhythmias. The role of efferent and afferent connections in the heart-brain axis is considered, with the mechanisms by which emotional responses promote arrhythmias illustrated by inherited cardiac conditions. Novel therapeutic targets for intervention in the autonomic nervous system are considered.
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