Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aldehydes and Ketones with Water: Hydrate Formation01:20

Aldehydes and Ketones with Water: Hydrate Formation

3.3K
An oxygen-based nucleophile, like water, can undergo addition reactions with aldehydes and ketones. The reaction leads to the formation of hydrates, also referred to as 1,1-diols or geminal diols.
The formation of hydrates is a reversible reaction. Hydrate formation is influenced by steric and electronic factors accompanying the alkyl substituents on the carbonyl group: The rate of hydrate formation increases with a decrease in the number of alkyl groups attached to the carbonyl carbon. Hence,...
3.3K
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide02:44

Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

10.4K
Alkenes are converted to 1,2-diols or glycols through a process called dihydroxylation. It involves the addition of two hydroxyl groups across the double bond with two different stereochemical approaches, namely anti and syn. Dihydroxylation using osmium tetroxide progresses with syn stereochemistry.
10.4K
Catalysis02:50

Catalysis

27.1K
The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.
27.1K
Reduction of Alkenes: Asymmetric Catalytic Hydrogenation02:17

Reduction of Alkenes: Asymmetric Catalytic Hydrogenation

3.4K
Catalytic hydrogenation of alkenes is a transition-metal catalyzed reduction of the double bond using molecular hydrogen to give alkanes. The mode of hydrogen addition follows syn stereochemistry.
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
3.4K
Thermal Electrocyclic Reactions: Stereochemistry01:17

Thermal Electrocyclic Reactions: Stereochemistry

2.0K
The stereochemistry of electrocyclic reactions is strongly influenced by the orbital symmetry of the polyene HOMO. Under thermal conditions, the reaction proceeds via the ground-state HOMO.
Selection Rules: Thermal Activation
Conjugated systems containing an even number of π-electron pairs undergo a conrotatory ring closure. For example, thermal electrocyclization of (2E,4E)-2,4-hexadiene, a conjugated diene containing two π-electron pairs, gives trans-3,4-dimethylcyclobutene.
2.0K
Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration02:34

Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration

8.5K
The rate of acid-catalyzed hydration of alkenes depends on the alkene's structure, as the presence of alkyl substituents at the double bond can significantly influence the rate.
8.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spin-State Transition in Heterometal-Bridged Cu-MnN<sub>4</sub> Motifs Overcomes Activity-Stability Trade-Off for Ultra-Stable Zinc-Air Batteries.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Efficient seawater electrolysis for hydrogen production with a NiS<sub>2</sub>-stabilized 1T-MoS<sub>2</sub> catalyst.

Chemical communications (Cambridge, England)·2026
Same author

Fluorine-Mediated Engineering of Stable High-Valence Single-Atom Catalysts.

Angewandte Chemie (International ed. in English)·2026
Same author

Large-scale synthesis of zinc oxide-supported indium single-atom catalysts for efficient electrocatalytic CO<sub>2</sub> reduction reaction.

Nanoscale·2026
Same author

Surface reconstruction of Cu(OH)<sub>2</sub> nanowire during electrocatalytic acetonitrile reduction to ethylamine.

Chemical communications (Cambridge, England)·2026
Same author

Portrayed the development of activated T cell to exhausted T cell based on the ratio of CD28 to CTLA4.

Cancer immunology, immunotherapy : CII·2026

Related Experiment Video

Updated: Jul 24, 2025

Developing Photosensitizer-Cobaloxime Hybrids for Solar-Driven H2 Production in Aqueous Aerobic Conditions
10:21

Developing Photosensitizer-Cobaloxime Hybrids for Solar-Driven H2 Production in Aqueous Aerobic Conditions

Published on: October 5, 2019

8.4K

Cyclodextrin-supported Co(OH)2 Clusters as Electrocatalysts for Efficient and Selective H2 O2 Synthesis.

Defeng Qi1, Jie Xu2, Yitong Zhou3

  • 1Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Department of Chemistry, School of Science, Tianjin University, Tianjin, 300072, P. R. China.

Angewandte Chemie (International Ed. in English)
|July 5, 2023
PubMed
Summary

Novel cyclodextrin-supported cobalt hydroxide (Co(OH)2) cluster catalysts efficiently produce hydrogen peroxide (H2O2) via the 2-electron oxygen reduction reaction (ORR). This offers a promising strategy for industrial H2O2 synthesis with high yield and selectivity.

Keywords:
Co(OH)2 ClusterCyclodextrinH2O2 ProductionSelectivityYield

More Related Videos

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction
10:57

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction

Published on: April 10, 2018

18.3K
Author Spotlight: Design and Evaluation of Au-Electroplated Carbon Fiber Cloth Electrodes for Hydrogen Peroxide Fuel Cells
06:39

Author Spotlight: Design and Evaluation of Au-Electroplated Carbon Fiber Cloth Electrodes for Hydrogen Peroxide Fuel Cells

Published on: October 20, 2023

2.9K

Related Experiment Videos

Last Updated: Jul 24, 2025

Developing Photosensitizer-Cobaloxime Hybrids for Solar-Driven H2 Production in Aqueous Aerobic Conditions
10:21

Developing Photosensitizer-Cobaloxime Hybrids for Solar-Driven H2 Production in Aqueous Aerobic Conditions

Published on: October 5, 2019

8.4K
Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction
10:57

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction

Published on: April 10, 2018

18.3K
Author Spotlight: Design and Evaluation of Au-Electroplated Carbon Fiber Cloth Electrodes for Hydrogen Peroxide Fuel Cells
06:39

Author Spotlight: Design and Evaluation of Au-Electroplated Carbon Fiber Cloth Electrodes for Hydrogen Peroxide Fuel Cells

Published on: October 20, 2023

2.9K

Area of Science:

  • Electrochemistry
  • Materials Science
  • Catalysis

Background:

  • Cobalt-based catalysts are promising for the 2-electron oxygen reduction reaction (ORR).
  • Existing Co-based catalysts lack high production yield rates for industrial hydrogen peroxide (H2O2) synthesis.
  • Efficient and selective electrocatalysts are needed for sustainable H2O2 production.

Purpose of the Study:

  • To develop novel Co-based catalysts for efficient H2O2 production.
  • To investigate the catalytic performance and stability of cyclodextrin-supported Co(OH)2 clusters.
  • To understand the mechanism underlying the enhanced catalytic activity using theoretical calculations.

Main Methods:

  • Synthesis of cyclodextrin-supported Co(OH)2 cluster catalysts using a mild and facile method.
  • Electrochemical evaluation of H2O2 selectivity, stability, and production yield rate in an H-type electrolytic cell.
  • Density Functional Theory (DFT) calculations to elucidate the reaction mechanism and electronic structure.

Main Results:

  • The novel catalyst achieved remarkable H2O2 selectivity (94.2%–98.2%) and good stability (99% activity retention after 35 hours).
  • An ultra-high H2O2 production yield rate of 5.58 mol g(catalyst)-1 h-1 was recorded.
  • DFT calculations revealed that cyclodextrin enhances the Co(OH)2 electronic structure, optimizing OOH* intermediate adsorption and increasing the activation energy barrier for dissociation.

Conclusions:

  • Cyclodextrin-supported Co(OH)2 cluster catalysts demonstrate significant potential for industrial H2O2 production.
  • The catalyst design strategy offers a valuable approach for developing high-performance Co-based electrocatalysts.
  • Optimized electronic structure and intermediate adsorption are key to achieving high reactivity and selectivity in the 2 e- ORR for H2O2 synthesis.