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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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Updated: Jul 24, 2025

A Micro-CT-based Method for Characterizing Lesions and Locating Electrodes in Small Animal Brains

A Micro-CT-based Method for Characterizing Lesions and Locating Electrodes in Small Animal Brains

Published on: November 8, 2018

[An unusual brain lesion].

Alia Zehani¹, Khalil Ghedira², Slim Haouet¹

¹Service d'anatomie pathologique, hôpital La Rabta, faculté de médecine de Tunis. université de Tunis El Mana, Tunisie.

Annales De Pathologie

|July 5, 2023

Summary

This summary is machine-generated.

A rare case of brain aspergillosis in an immunocompetent adult presented with severe neurological symptoms and vision loss. Fungal hyphae were identified in excised brain tissue, leading to a fatal outcome despite surgical intervention.

Keywords:

Aspergillose Aspergillosis Brain Cerveau Prognosis Pronostic

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Area of Science:

Neurology
Mycology
Pathology

Background:

Brain infections are uncommon in immunocompetent individuals.
Fungal infections of the central nervous system (CNS) require prompt diagnosis and treatment.

Observation:

A 31-year-old man presented with headache, vision loss, proptosis, papilledema, and fever.
Brain imaging revealed a right temporobasal lesion.
Histopathology showed glial tissue with inflammation, giant cells, and septate hyphae.

Findings:

Microscopic examination confirmed invasive fungal elements consistent with Aspergillus species.
Periodic acid-Schiff (PAS) staining highlighted the fungal hyphae within the brain tissue.
The patient experienced a fatal postoperative course.

Implications:

This case highlights the potential for aggressive fungal brain infections even in immunocompetent hosts.
Early recognition and aggressive antifungal therapy are crucial for managing CNS aspergillosis.
Further research into diagnostic and therapeutic strategies for CNS aspergillosis is warranted.