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Related Experiment Videos

High plasma urea concentrations in collodion babies.

D W Beverley, D Wheeler

    Archives of Disease in Childhood
    |July 1, 1986
    PubMed
    Summary

    Two infants with collodion membrane experienced elevated plasma urea levels after topical treatment with a 10% urea and 5% lactic acid product. This highlights a potential risk of systemic absorption with such dermatological preparations.

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    Area of Science:

    • Neonatal dermatology
    • Pediatric pharmacology
    • Dermatological product safety

    Background:

    • Collodion membrane is a rare congenital condition affecting newborns.
    • Topical treatments are often used for collodion membrane management.
    • Systemic absorption of topical agents in neonates requires careful consideration.