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Anorectal function after low anterior resection for carcinoma.

I K Pedersen, J Christiansen, K Hint

Annals of Surgery

|August 1, 1986

Summary

Low anterior resection (LAR) for rectal cancer moderately impacts anorectal function, with persistent reflex abnormalities and reduced rectal compliance observed up to 12 months post-surgery.

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Area of Science:

Colorectal Surgery
Gastrointestinal Physiology
Oncology

Background:

Rectal cancer treatment often involves surgery impacting anorectal function.
Low anterior resection (LAR) is a common surgical approach for rectal tumors.
Understanding functional outcomes post-LAR is crucial for patient recovery.

Purpose of the Study:

To evaluate anorectal function in patients undergoing low anterior resection (LAR) for rectal cancer.
To compare functional outcomes before and after surgery.
To assess the long-term effects of LAR on rectal compliance and rectoanal reflexes.

Main Methods:

Prospective study of 13 rectal cancer patients treated with LAR.
Comparison with 13 age- and sex-matched healthy controls.

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Assessment of anal pressures, rectoanal inhibitory reflex, and rectal compliance at baseline and 3, 12 months post-op.

Main Results:

Anal resting and squeeze pressures showed only moderate decreases post-LAR, with some recovery at 12 months.
Significant abnormalities in the rectoanal inhibitory reflex persisted in most patients up to 12 months.
Rectal compliance was reduced pre-operatively and remained low at 3 months, returning to baseline by 12 months in most patients.

Conclusions:

Low anterior resection (LAR) leads to moderate, but often persistent, anorectal functional deficits.
Rectoanal reflex abnormalities and reduced rectal compliance are common sequelae post-LAR.
Further research may explore strategies to improve functional recovery after LAR for rectal cancer.