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Published on: June 11, 2012
Clinical activities that contributed to the effectiveness of a cardiologist-pharmacist collaborative care model in
Zheng Kang Lum1, Kwee Keng Kng2, Cynthia Ee Mei Goh2
1Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore.
Insights
Pharmacist-involved collaborative care significantly improved glycated haemoglobin (HbA1c) in Type 2 diabetes patients. Health education and medication adjustments were key drivers of this improvement.
Area of Science:
- Endocrinology
- Pharmacotherapy
- Cardiovascular Medicine
Background:
- Type 2 diabetes management requires continuous monitoring of glycated haemoglobin (HbA1c).
- Pharmacist-involved collaborative care (PCC) models are emerging as a strategy to improve patient outcomes.
- The association between PCC, clinical activities, and HbA1c changes needs further elucidation.
Purpose of the Study:
- To evaluate the change in HbA1c in patients receiving PCC compared to cardiologist care (CC).
- To identify clinical activities associated with HbA1c improvement.
- To explore moderators influencing the PCC-HbA1c relationship.
Main Methods:
- Retrospective cohort study of 420 adults with Type 2 diabetes and cardiovascular disease over 12 months.
- 1:1 matching of PCC patients with CC patients based on baseline HbA1c.
- Linear mixed models and linear regression analyzed HbA1c changes and associated clinical activities.
Main Results:
- The PCC group showed a significant mean HbA1c decrease of -0.4% at 6 and 12 months, compared to -0.1% and -0.2% in the CC group (P<0.001).
- Higher frequencies of lifestyle counseling, health education, medication adherence reinforcement, and problem resolution were observed in the PCC group (P<0.001).
Conclusions:
- Pharmacist-involved collaborative care leads to significant improvements in HbA1c for Type 2 diabetes patients.
- Health education and medication adjustments are critical components driving HbA1c reduction within PCC.
- PCC offers a valuable model for enhancing diabetes management and cardiovascular health.
Objectives:
The primary objectives of this study were to evaluate the change in glycated haemoglobin (HbA1c) and its association to clinical activities. The secondary objective was to elucidate moderators of the relationship between pharmacist-involved collaborative care (PCC) and change in HbA1c.
Methods:
This study was a retrospective cohort study conducted in a tertiary hospital over 12 months. Individuals with Type 2 diabetes, aged ≥21 years with established cardiovascular diseases were included while individuals with incomplete care documentation or missing data related to cardiovascular diseases were excluded. Individuals under the care of PCC were matched 1:1 based on baseline HbA1c with an eligible person who received care from the cardiologists (CC). Changes in mean HbA1c were analysed using linear mixed model. Linear regression was used to determine clinical activities that associated with improvement in HbA1c. Moderation analyses were conducted using the MacArthur framework.
Key Findings:
A total of 420 participants (PCC:210, CC:210) were analysed. The mean age of the participants was 65.6 ± 11.1 years, with the majority being male and Chinese. The mean HbA1c among participants in the PCC group decreased significantly after 6 months (PCC: -0.4% versus CC: -0.1%, P = 0.016), with maintenance of improvement at 12 months (PCC: -0.4% versus CC: -0.2%, P < 0.001). Frequencies of lifestyle counselling, reinforcement of visits to healthcare providers, health education, resolution of drug-related problems, emphasis on medication adherence, dose adjustments and advice on self-care techniques were significantly higher in the intervention group (P < 0.001).
Conclusion:
Improvements in HbA1c were associated with the provision of health education and medication adjustments.
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