Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intraocular pressure elevation after pupillary dilation in open angle glaucoma.

B R Shaw, R A Lewis

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |August 1, 1986
    PubMed
    Summary

    Pupillary dilation can cause acute intraocular pressure elevation in primary open angle glaucoma patients. Miotics were a significant risk factor, indicating a potential hazard with routine dilation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Prostaglandin release in a perfused human anterior segment model.

    Journal of glaucoma·2009
    Same author

    X-ray refraction effects: application to the imaging of biological tissues.

    The British journal of radiology·2003
    Same author

    Ethylene glycol intoxication: electrophysiological studies suggest a polyradiculopathy.

    Neurology·2002
    Same author

    Diagnostic DNA testing for X-linked ocular albinism (OA1) with a hierarchical mutation screening protocol.

    Genetic testing·2002
    Same author

    A prospective, open-label treatment trial to compare the effect of IFNbeta-1a (Avonex), IFNbeta-1b (Betaseron), and glatiramer acetate (Copaxone) on the relapse rate in relapsing--remitting multiple sclerosis: results after 18 months of therapy.

    Multiple sclerosis (Houndmills, Basingstoke, England)·2002
    Same author

    Evaluation of the ELOVL4 gene in patients with age-related macular degeneration.

    Ophthalmic genetics·2002

    Area of Science:

    • Ophthalmology
    • Glaucoma Research
    • Ocular Pharmacology

    Background:

    • Pupillary dilation is common in ophthalmology.
    • Acute intraocular pressure (IOP) elevation can occur post-dilation in primary open angle glaucoma (POAG) patients.
    • Miotics are frequently used in POAG management.

    Purpose of the Study:

    • To assess the frequency and severity of IOP elevation after pupillary dilation.
    • To identify risk factors for IOP elevation post-dilation in POAG.
    • To compare post-dilation IOP changes with post-operative IOP changes.

    Main Methods:

    • Retrospective study of 60 POAG patients (116 eyes).
    • Dilation using 2.5% phenylephrine hydrochloride and 1% tropicamide.
    • IOP measurement one hour post-dilation and compared with post-argon laser trabeculoplasty IOP.

    Related Experiment Videos

    Main Results:

    • Significant IOP elevation (>5 mm Hg) in 32% of eyes.
    • Marked IOP elevation (>10 mm Hg) in 12% of eyes.
    • Miotics identified as the only significant risk factor for IOP elevation.

    Conclusions:

    • Routine pupillary dilation poses a potential hazard for POAG patients.
    • Miotics may increase the risk of IOP elevation following dilation.
    • Further investigation into safe dilation protocols for POAG is warranted.