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Thermoablative Techniques to Treat Excessive Central Airway Collapse
Sidhu P Gangadharan1, Fleming Mathew1
1Division of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center, W/DC 201, 185 Pilgrim Road, Boston, MA 02215, USA.
Thoracic Surgery Clinics
|July 6, 2023
Summary
Excessive central airway collapse (ECAC) involves airway narrowing during exhalation. While standard treatments exist, thermoablative bronchoscopic therapies show promise as alternatives, though further research is needed.
Area of Science:
- Pulmonology and Respiratory Medicine
- Interventional Bronchoscopy
Background:
- Excessive central airway collapse (ECAC) is a condition of expiratory narrowing of the trachea and mainstem bronchi.
- It can stem from Tracheobronchomalacia (TBM) or Excessive Dynamic Airway Collapse (EDAC).
Purpose of the Study:
- To review current management strategies for ECAC.
- To explore the potential of thermoablative bronchoscopic treatments as an alternative to surgery.
Main Methods:
- Review of existing literature on ECAC management.
- Discussion of standard treatments including medical management and surgical options like tracheobronchoplasty.
- Exploration of thermoablative techniques such as Argon plasma coagulation (APC) and laser therapies (KTP, Ho:YAP).
Main Results:
- Standard care involves treating underlying conditions (asthma, COPD, GERD).
- Stent trials and tracheobronchoplasty are options for severe, medically refractory cases.
- Thermoablative bronchoscopic treatments are emerging as a promising alternative to surgery.
Conclusions:
- Further clinical research is essential to validate the safety and efficacy of thermoablative bronchoscopic treatments for ECAC in humans.
- These novel techniques may offer a less invasive option for managing severe central airway collapse.
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