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Updated: Jul 24, 2025
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Selective venous sampling in primary hyperparathyroidism caused by ectopic parathyroid gland: a case report and
Xubin Yang1, Xueyan Chen1, Huan Xu1
1Department of Endocrinology and Metabolic Diseases, Guangdong Provincial Key Laboratory of Diabetology, the Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road, Guangzhou, 510630, Guangdong Province, China.
Background:
As an invasive technique, selective venous sampling (SVS) is considered a useful method to identify a lesion's location to increase the success rate of secondary surgery in patients with primary hyperparathyroidism (pHPT) caused by ectopic parathyroid adenomas.
Case Presentation:
We present a case of post-surgical persistent hypercalcemia and elevated parathyroid hormone (PTH) levels in a 44-year-old woman with previously undetected parathyroid adenoma. An SVS was then performed for further localization of the adenoma, as other non-invasive methods showed negative results. After SVS, an ectopic adenoma was suspected in the sheath of the left carotid artery, previously considered as a schwannoma, and was pathologically confirmed after the second operation. Postoperatively, the patient's symptoms disappeared and serum levels of PTH and calcium normalized.
Conclusions:
SVS can provide precise diagnosis and accurate positioning before re-operation in patients with pHPT.
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