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Primary Retroperitoneal Mucinous Cystadenocarcinoma: A Case Report.
Saroja Devi Geetha1, Louis Kavoussi2, Rebecca Thomas1
1Pathology, Northwell Health, Greenvale, USA.
Cureus
|July 7, 2023
Summary
Retroperitoneal mucinous cystadenocarcinoma is a rare tumor. This case highlights its unusual presentation and emphasizes its consideration in diagnosing retroperitoneal cystic lesions.
Area of Science:
- Gastroenterology
- Gynecologic Oncology
- Urologic Oncology
Background:
- Mucinous neoplasms frequently occur in the ovaries and pancreas.
- Retroperitoneal occurrence of mucinous neoplasms is rare.
Observation:
- A 54-year-old female presented with right flank pain and a renal mass suspicious for renal cell carcinoma.
- Imaging revealed an 8.6 × 7.9 cm retroperitoneal mass.
- Elevated cancer antigen 125 (CA 125) was noted, while carbohydrate antigen 19-9 (CA 19-9) and cancer embryonic antigen (CEA) were within normal limits.
Findings:
- Surgical resection identified a 10.0 × 7.0 × 7.0 cm retroperitoneal cystic mass.
- Histopathology confirmed mucinous cystadenocarcinoma with ovarian-type stroma and invasive carcinoma components.
- The tumor was unattached to the kidney.
Implications:
- This case underscores the importance of considering mucinous cystadenocarcinoma in the differential diagnosis of retroperitoneal cystic lesions.
- Early recognition and diagnosis are crucial for appropriate management of this rare entity.

