Antiviral activity of silver nanoparticles against the influenza A virus
Krystyna Naumenko1, Svitlana Zahorodnia1, Calin V Pop2
1Zabolotny Institute of Microbiology and Virology, The National Academy of Sciences of Ukraine, st. Academician Zabolotny, 154, 03143, Kyiv, Ukraine.
Abstract:
Viral infections occupy an essential place in modern medicine, particularly a large group of diseases caused by the influenza viruses. They are rapidly transmitted and mutate quickly, which can lead to significant socio-economic consequences. Silver nanoparticles (AgNPs) are considered to be an effective antimicrobial agent. This study shows that they have strong antiviral properties against the influenza A virus infection. Their absence of cytotoxicity at inhibitory concentrations demonstrates that they could be an effective antiviral agent against this virus. As AgNPs inhibit the influenza A virus replication and spread, they could also be successfully used as a post-infection virostatic agent.


