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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Related Experiment Video

Updated: Jul 24, 2025

Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells
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Optic nerve sheath fenestration: A second lease at sight.

Mukesh Sharma1, Aishwarya Chhabra2, Nupur Raina3

  • 1Medical Director, Department of Opthalmology, Centre for Sight Hospital, Jaipur, Rajasthan, India.

Indian Journal of Ophthalmology
|July 7, 2023
PubMed
Summary

Optic nerve sheath fenestration surgery effectively treats vision-threatening optic disc edema. This procedure improves visual acuity and resolves associated symptoms in patients with various underlying causes.

Keywords:
Cerebrospinal fluidheadacheidiopathic intracranial hypertensionpapilledemapseudotumor cerebrivision

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Area of Science:

  • Ophthalmology
  • Neurosurgery

Background:

  • Optic disc edema can lead to vision loss.
  • Various etiologies can cause optic disc edema.

Purpose of the Study:

  • To evaluate the safety and efficacy of optic nerve sheath fenestration (ONSF) surgery.
  • To assess ONSF in patients with optic disc edema from diverse causes.

Main Methods:

  • Retrospective review of 18 eyes from 15 patients undergoing ONSF.
  • Analysis of visual acuity, visual fields, optic disc edema resolution, diplopia, and headache.

Main Results:

  • Significant improvement in visual acuity in operated eyes (p < 0.005) and contralateral eyes (p < 0.05).
  • Idiopathic intracranial hypertension was the most common cause (80%).
  • Observed benefits include resolved optic disc edema, improved visual fields, and reduced diplopia and headache.

Conclusions:

  • Early ONSF is an effective treatment for optic disc edema.
  • The surgery helps resolve symptoms associated with optic disc edema.