Search research articles

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Efficacy and safety of efgartigimod PH20 SC for Sjögren's disease-associated dryness: study protocol for an investigator-initiated, multicenter, phase 2, randomized, double-blind, placebo-controlled trial (OASIS study).

Frontiers in medicine·2026

Same author

AI-Powered Histology for Molecular Profiling in Brain Tumors: Toward Smart Diagnostics from Tissue.

Cancers·2026

Same author

Impact of hypoalbuminemia severity on total teicoplanin concentrations after 3 days loading dose: a retrospective observational study.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy·2025

Same author

Correction to: Background removal for debiasing computer-aided cytological diagnosis.

International journal of computer assisted radiology and surgery·2024

Same author

Differences in Electroencephalography Power Levels between Poor and Good Performance in Attentional Tasks.

Brain sciences·2024

Same author

Background removal for debiasing computer-aided cytological diagnosis.

International journal of computer assisted radiology and surgery·2024

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jul 24, 2025

Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots

Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots

Published on: February 11, 2022

An effective salivation-facilitating method for COVID-19 testing: An experimental study.

Misako Higashijima¹, Hiroyasu Shiozu², Tomoya Sakai³

¹Faculty of Rehabilitation Sciences, Nishi Kyushu University, Saga, Japan.

|July 7, 2023

Summary

This summary is machine-generated.

Plum pickle presence or consumption significantly increased saliva production in healthy adults, aiding coronavirus disease 2019 (COVID-19) testing. This method offers a simple way to improve saliva collection for diagnostic tests.

More Related Videos

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling

Published on: June 23, 2022

Forced Salivation As a Method to Analyze Vector Competence of Mosquitoes

Forced Salivation As a Method to Analyze Vector Competence of Mosquitoes

Published on: August 7, 2018

Related Experiment Videos

Last Updated: Jul 24, 2025

Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots

Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots

Published on: February 11, 2022

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling

Published on: June 23, 2022

Forced Salivation As a Method to Analyze Vector Competence of Mosquitoes

Forced Salivation As a Method to Analyze Vector Competence of Mosquitoes

Published on: August 7, 2018

Area of Science:

Biomedical Science
Diagnostic Testing
Salivary Diagnostics

Background:

Antigen test kits for coronavirus disease 2019 (COVID-19) are widely available but pose challenges for the elderly due to dry mouth.
Effective saliva collection is crucial for accurate COVID-19 diagnostic testing.

Purpose of the Study:

To investigate if a plum pickle can stimulate salivation for improved COVID-19 testing.
To assess the efficacy of plum pickle presentation and consumption in facilitating saliva production.

Main Methods:

Twenty healthy adult women were divided into two groups: pickle presentation vs. non-presentation and pickle eating vs. non-eating.
Saliva production was measured by recording the number of swallows in one minute using a swallowing test device with hyoid bone and thyroid cartilage sensors.

Main Results:

A significant increase in swallows (saliva production) was observed when participants were presented with plum pickle (P < .01).
Consuming plum pickle also led to a significant increase in swallows compared to non-consumption (P < .01).

Conclusions:

Plum pickle effectively facilitates salivation, potentially due to citric acid stimulation, saliva buffer capacity, and motor learning.
This technique offers a complementary method for efficient specimen collection in COVID-19 testing, avoiding risks associated with direct citric acid intake.
Further research is needed to validate this method in elderly populations within clinical settings.