Related Experiment Video

Updated: Jul 24, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

11.9K

Adverse birth outcomes and associated factors among newborns delivered in Sao Tome & Principe: A case‒control study

Alexandra Vasconcelos1, Swasilanne Sousa2, Nelson Bandeira3

  • 1Instituto de Higiene e Medicina Tropical (IHMT), Unidade de Clínica Tropical-Global Health and Tropical Medicine (GHTM), Universidade NOVA de Lisboa, Lisboa, Portugal.

Plos One
|July 7, 2023
PubMed

Insights

Adverse birth outcomes (ABOs) are linked to twin pregnancies and prolonged rupture of membranes. High-quality antenatal care (ANC) significantly reduces ABO risk in newborns.

Area of Science:

  • Neonatal Health
  • Obstetrics
  • Public Health

Background:

  • Adverse birth outcomes (ABOs) increase newborn mortality and long-term health issues.
  • Identifying factors associated with ABOs is crucial for effective interventions.
  • This study focused on ABOs in Sao Tome & Principe, a resource-limited sub-Saharan African country.

Purpose of the Study:

  • To assess factors associated with adverse birth outcomes (ABOs) in newborns.
  • To inform targeted interventions in resource-constrained settings.

Main Methods:

  • A hospital-based, unmatched case-control study was conducted.
  • Newborns with one or more ABOs were cases; healthy newborns were controls.
  • Data were collected via interviews and medical records; multivariable logistic regression was used.

Main Results:

  • Twin pregnancy (aOR 4.92), prolonged rupture of membranes (aOR 3.43), and meconium-stained fluid (aOR 1.59) were significantly associated with ABOs.
  • Eight or more antenatal care (ANC) contacts were protective against ABOs (aOR 0.33).

Conclusions:

  • Modifiable factors linked to ABOs necessitate cost-effective interventions.
  • Prioritizing high-quality ANC is essential.
  • Twin pregnancies and intrapartum complications require prompt attention and follow-up.
Abstract

More Related Videos

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

86.1K
Biochemical Measurement of Neonatal Hypoxia13:13

Biochemical Measurement of Neonatal Hypoxia

Published on: August 24, 2011

14.1K

Related Concept Videos

Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.5K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.0K
Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
1.1K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.0K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
148
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K