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Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
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Lyme borreliosis in pediatric population: Clinical, diagnostic and therapeutic features

Ana Rubio Granda1, María Fernández-Miaja1, Mercedes Rodríguez Pérez2

  • 1Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain.

Enfermedades Infecciosas Y Microbiologia Clinica (English Ed.)
|July 7, 2023
PubMed

Insights

Pediatric Lyme borreliosis (LB) presents unique challenges. This study highlights the diagnostic and treatment specifics in children, showing a favorable prognosis with timely antimicrobial therapy.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Clinical Research

Background:

  • Lyme borreliosis (LB) in children is not well-studied.
  • Pediatric LB has unique characteristics and diagnostic challenges.

Purpose of the Study:

  • To describe the clinical features of pediatric Lyme borreliosis.
  • To outline the diagnostic and therapeutic approaches for children with LB.

Main Methods:

  • Retrospective descriptive study.
  • Included patients up to 14 years old with suspected or confirmed LB from 2015-2021.

Main Results:

  • 18 confirmed LB cases among 21 patients; median age 6.4 years.
  • Common symptoms included neurological (e.g., facial nerve palsy) and dermatological (erythema migrans).
  • Serology confirmed diagnosis in 83.3%; 94.4% received antimicrobial treatment for a median of 21 days, with full recovery.

Conclusions:

  • Diagnosing LB in children is complex and has specific clinical and therapeutic features.
  • Pediatric Lyme borreliosis has a positive prognosis with appropriate treatment.
Abstract

Keywords:
BorreliosisBorreliosis de LymeEnfermedad de LymeLyme borreliosisLyme diseasePediatricsPediatríaSerologySerología

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