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Updated: Jul 24, 2025

Qualitative Identification of Carboxylic Acids, Boronic Acids, and Amines Using Cruciform Fluorophores
Published on: August 19, 2013
Supramolecular fluorescent probe based on a host-guest complex for amino acids recognition and detection in aqueous
Xing-Xing Chen1, Shu-Zhen Huang2, Ru-Pei Yang2
1Department College of Tobacco Science, Guizhou University, Guiyang 550025, China; Guizhou Provincial Key Laboratory for Tobacco Quality, College of Tobacco Science, Guizhou Univ., Guiyang 550025, China.
Abstract:
A supramolecular fluorescent probe based on a host-guest complex has been developed for amino acid recognition and detection in aqueous solution. Cucurbit[7]uril (Q[7]) with 4-(4-dimethylamino-styrene) quinoline (DSQ) formed a fluorescent probe (DSQ@Q[7]). The DSQ@Q[7] fluorescent probe nearly generated changes in fluorescence in response to four amino acids (arginine, histidine, phenylalanine and tryptophan). These changes were attributed to the host-guest interaction between DSQ@Q[7] and amino acids, which occurred as a consequence of the subtle cooperation of ionic dipole and hydrogen bonding. Linear discriminant analysis showed that the fluorescent probe could recognize and distinguish four amino acids, and a mixture with different concentration ratios could be well categorized in ultrapure water and tap water.
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