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The relationship between functional constipation and overweight/obesity in children: a systematic review and

Gui Na Wang1, Kun Zhang1, Yi Yun Xiong1

  • 1Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.

Pediatric Research
|July 8, 2023
PubMed

Insights

Children with functional constipation face an increased risk of obesity, affecting both boys and girls. This association is particularly noted in developed nations, highlighting the need for early intervention.

Area of Science:

  • Pediatric Gastroenterology
  • Childhood Obesity Research
  • Public Health

Background:

  • Contradictory findings exist regarding the link between functional constipation and obesity in children.
  • This study aims to clarify the association between these pediatric conditions.

Approach:

  • A systematic review and meta-analysis was conducted.
  • Searched four major databases (PubMed, Embase, CENTRAL, Web of Science) until September 2022.
  • Included nine studies with 7444 participants, adhering to PRISMA guidelines.

Key Points:

  • Functional constipation significantly increases obesity risk in both boys and girls.
  • A notable association exists between overweight/obesity and functional constipation in children and adolescents.
  • This link is more pronounced in developed countries compared to developing ones.

Conclusions:

  • Functional constipation is a risk factor for obesity in pediatric populations.
  • Obesity is associated with an increased risk of functional constipation, especially in developed countries.
  • Further research is recommended for early detection and optimized treatment strategies.
Abstract

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